Nuances of Combining Retinol and Vitamin C in Skincare

Combining retinol and vitamin C in your skincare routine can be beneficial. Often, a small percentage of stable vitamin C is added to retinol serums to stabilize them and enhance retinol’s effects. However, there are nuances to using these active ingredients together that are not always discussed.

  1. Allow Skin to Adjust to Retinol First
    • Let your skin get used to retinol before introducing vitamin C. It’s not advisable to start using two new actives simultaneously.
  2. Separate by Time of Day
    • Use retinol in the evening and vitamin C in the morning. This makes more sense for the actives themselves.
  3. Avoid Combining High-Irritation Potential Products
    • It’s better not to combine high-percentage ascorbic acid (vitamin C) with retinol in your routine due to their potential to cause irritation.
  4. Individual Skin Reactions
    • Retinol can change your skin’s reaction to familiar products. Sometimes, a specific combination of retinol and vitamin C might not suit your skin. Often, vitamin C is blamed for breakouts or irritation, but the actual culprit might be the interaction between the products. Patch tests and monitoring skin reactions are crucial.

Specific Cautions

  • Vitamin C and Benzoyl Peroxide
    • Do not use vitamin C with benzoyl peroxide in parallel, as this combination has a high risk of irritating the skin.
  • Vitamin C and AHA Acids
    • Vitamin C can be used alongside AHA acids but avoid high percentages of azelaic acid. While a 10% azelaic acid serum works well with vitamin C, higher concentrations (15-20%) found in pharmacy gels can increase the risk of skin irritation. If you apply a high-percentage azelaic acid gel at night, avoid using vitamin C in the morning.

By following these guidelines, you can effectively and safely integrate retinol and vitamin C into your skincare routine.


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